Ingredient

MEA O-PHENYLPHENATE

Substance information

"MEA" refers to a monoethanolamine salt or an amide of monoethanolamine (2-aminoethanol). "Phenyl" mostly refers to phenol as alcoholic component or generally the phenyl group as aromatic hydrocarbon residue.

Function(s) of this ingredient in cosmetic products

ANTIMICROBIAL

Helps control the growth of micro-organisms (eg bacteria and fungi)

Origin

synthetic

Occurrence in cosmetics

MEA-o-phenylphenate is no longer used in cosmetic products.

Why are we talking about it?

Annex III of the European Cosmetic Products Regulation sets maximum limits for the level of nitrosamines in mono- and trialkylamines and -alkanolamines and in fatty acid dialkylamines and dialkanolamides. Formation of relevant nitrosamines can occur by the reaction of secondary amino compounds contained as impurities in such ingredients with nitrosating agents (with nitrites; nitrosation reaction). Nitrosamines, which are potentially carcinogenic components, may therefore appear as unavoidable traces in the cosmetic product after its manufacture. The facts: There is a global strategy against the formation of nitrosamines, relying on cosmetic regulations and the recommendations of professional bodies (1 and 2). This strategy covers the raw materials (whose purity is controlled to limit impurities), the manufacturing process, storage and the finished product. Choosing ingredients with low potential for nitrosation is also critical (2). In order to guarantee the effectiveness of these measures, nitrosamines levels are measured in the raw materials and in the finished product. To limit the formation of nitrosamines, it is also possible to add ingredients to the formula which will prevent this reaction. Cosmetic formulation is a rigorous science with many constraints, which the issue of nitrosamine management perfectly illustrates. Key points to take away: The formation of nitrosamines is a very well regulated issue in the manufacture of cosmetic products, from raw materials to finished products. All precautions are taken to avoid their formation. Sources: (1) Opinion of the European Scientific Committee on Consumer Safety (SCCS): SCCS/1458/11 - Opinion on Nitrosamines and Secondary Amines in Cosmetic Products: https://ec.europa.eu/health/scientific_committees/consumer_safety/docs/sccs_o_090.pdf (2) COSMETICS EUROPE: Technical guidance document on minimising and determining nitrosamines in cosmetics, 2009: https://cosmeticseurope.eu/download/TjBjaHR5ekxhQ0Vxbkc1eEtKU2NTdz09

Belongs to the following substance groups

Antibacterial ingredients

Regulating cosmetics

Cosmetics Ingredients are subject to regulation. Please note, different regulations may apply to cosmetic ingredients outside the EU.

Understanding your cosmetics

How are cosmetics kept safe in Europe?

Strict laws make sure that cosmetics and personal care products sold in the European Union are safe for people to use. Companies, national and European regulatory authorities share the responsibility of keeping cosmetic products safe.

What should I know about endocrine disruptors?

Some ingredients used in cosmetic products have been claimed to be ‘endocrine disruptors’ because they have the potential to mimic some of the properties of our hormones. Just because something has the potential to mimic a hormone does not mean it will disrupt our endocrine system. Many substances, including natural ones, mimic hormones but very few, and these are mostly potent medicines, have ever been shown to cause disruption of the endocrine system. The rigorous product safety assessments by qualified, scientific experts that companies are legally obliged to carry out cover all potential risks, including potential endocrine disruption.

Are cosmetics tested on animals? No!

In the European Union, testing cosmetics on animals has been fully banned since 2013. Over the last 30 years, long before a ban was in place, the cosmetics and personal care industry has invested in research and development to pioneer alternatives to animal testing tools to assess the safety of cosmetics ingredients and products.

What about allergens in cosmetics?

Many substances, natural or man-made, have the potential to cause an allergic reaction. An allergic reaction occurs when a person’s immune system reacts to substances that are harmless to most people. A substance that causes an allergic reaction is called an allergen. Cosmetics and personal care products may contain ingredients that can be allergenic for some people. This does not mean that the product is not safe for others to use.

Database

Cosmetics matter to people and play an important role in our everyday life. On average European consumers use over seven different cosmetics daily. You too? It’s only natural that you want to know more about the ingredients in those products.

In the digital world we live in, there’s a deluge of information on cosmetics. However, it can be difficult to know which sources are reliable. COSMILE Europe is a European cosmetic ingredient database that offers reliable, verified and scientifically supported information on almost 30,000 ingredients used in cosmetics.

This database will help you understand why certain ingredients are in your cosmetic products; which properties they have and much more. The database is currently available in fourteen languages with more to come.

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